Scooby-Doo and Guess Who?

The Mystery Inc. crew reconvenes to tackle a fresh set of standalone mysteries that often intersect with well-known figures from across entertainment, sports, science, and pop culture. Each episode pairs Fred, Daphne, Velma, Shaggy, and Scooby with a different celebrity guest who becomes involved in an odd case, whether it's a haunted theater, a strange artifact, or a bizarre sabotage. The cases lean toward lighthearted puzzles and humorous scares, with the gang using clues, traps, and teamwork to get to the bottom of things. Episode tone can shift from broad physical comedy to more classic clue-gathering, so each installment has its own rhythm. The series keeps things family friendly, letting younger viewers laugh and older fans enjoy nods to franchise history.

Premiering in 2019, the animated series reunites veteran voices Frank Welker, Matthew Lillard, Grey DeLisle, and Kate Micucci, combining the classic Mystery Inc. lineup with a rotating roster of celebrity guest stars across each season and modern sensibilities.

The series didn't collect major industry awards, but it became a notable entry in the Scooby-Doo catalogue, earning steady fan appreciation and occasional mentions in genre roundups for keeping the franchise visible and introducing playful celebrity cameos to a new generation, and steady fan engagement online and offline.

By bringing real-life celebrities into its plots, the show renewed a long-running Scooby tradition, producing memorable crossover moments that travel beyond the episodes into social conversation, helping the classic mystery format stay relevant to contemporary audiences, and it sometimes generated viral clips on social platforms.

Audience response has been favorable, reflected in a 7.994/10 vote average from 244 votes. Viewers praise its family-friendly mysteries, emphasis on teamwork and problem solving, comic timing, and the chemistry between the core cast and celebrity guests. Critics noted its fond nods to franchise history while keeping episodes brisk and accessible.