The Sarah Vaccine poster

The Sarah Vaccine

Movie 2021 10.0 /10
Directed by Sarah Sherman

The Sarah Vaccine tosses viewers into a neon-soaked, shock-comedy take on the pandemic era, centered on the anarchic performer Sarah Squirm. When public institutions fumble their response to a health crisis, Sarah vows a DIY cure that quickly escalates into absurd and explicit grotesquerie. The... Read more

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Streaming availability last verified: January 20, 2026

About The Sarah Vaccine

The Sarah Vaccine tosses viewers into a neon-soaked, shock-comedy take on the pandemic era, centered on the anarchic performer Sarah Squirm. When public institutions fumble their response to a health crisis, Sarah vows a DIY cure that quickly escalates into absurd and explicit grotesquerie. The film leans on exaggerated gore, toilet humor, and surreal set pieces to satirize fear, misinformation, and celebrity saviors, shifting from slapstick to body-horror in short order. Scenes favor vivid practical effects and bizarre sight gags over tight plotting, and Sherman's performance keeps the tone chaotic, oddly theatrical, so expect memorable images and gross-out jokes rather than a measured drama.

Released in 2021, The Sarah Vaccine was written, directed, and led by comedian Sarah Sherman, who plays the title role. It's an indie production with DIY design, punk-tinged music, and a small cast of Zach Holmes, Leah Hennessey, Ruby McCollister.

The Sarah Vaccine did not receive major industry awards or mainstream nominations, and it wasn't part of awards season conversation. Its extreme gore and scatological humor put it outside most juried recognition, though it may register with cult cinephile circles. It drew niche attention online from fans of transgressive comedy.

Its vivid colors, relentless shock humor, and willingness to mix bodily horror with satire help it stand out for viewers who seek boundary-pushing comedy. Punk-infused musical bits and gross-out set pieces linger in memory. Fans sometimes share its images, which can spark debate about limits and taste in comedy.

Critical response is limited, and available ratings are minimal, including a 10.0/10 from a single vote on one platform. Reactions are polarizing, with some admiring its fearless absurdity and others rejecting its excess. Themes include distrust of institutions, performative saviors, and outrageous physical humor, framed as satirical provocation rather than sober reflection. Expect split reactions online and offline.

Details

Release Date
May 07, 2021
User Ratings
1 votes
Type
Movie
Genres
Comedy

Cast

Sarah Sherman

Sarah Sherman

Sarah Squirm

Zach Holmes

Zach Holmes

L

Leah Hennessey

Punk Rock Singer

Ruby McCollister

Ruby McCollister

Punk Rock Singer 2

Director: Sarah Sherman

Frequently Asked Questions

The Sarah Vaccine is not currently available to stream, rent, or buy online in the US. Check back later for updates.

With a rating of 10.0/10 from 1 viewers, The Sarah Vaccine is highly recommended and considered excellent by most viewers.

The Sarah Vaccine tosses viewers into a neon-soaked, shock-comedy take on the pandemic era, centered on the anarchic performer Sarah Squirm. When public institutions fumble their response to a health crisis, Sarah vows a DIY cure that quickly escalates into absurd and explicit grotesquerie. The f...

The Sarah Vaccine stars Sarah Sherman, Zach Holmes, Leah Hennessey, and Ruby McCollister.

The Sarah Vaccine was directed by Sarah Sherman.

The Sarah Vaccine was released on May 07, 2021.

The Sarah Vaccine is a Comedy film.

No, The Sarah Vaccine is a fictional, surreal comedy created and performed by Sarah Sherman. It's a satirical, over-the-top take on pandemic fears rather than a factual account.

No, it's not appropriate for kids or viewers who are squeamish. The film includes excessive gore, poop, vomit, and blood and is aimed at adults who can handle extreme gross-out and shock humor.

It's billed as a comedy but leans heavily on horror and body-shock elements, so it's best described as a black comedy with strong horror vibes. If you like dark, surreal humor mixed with graphic visuals, this is the kind of film you should expect.

Yes, the film frames itself as a technicolor COVID nightmare and satirizes pandemic-era anxieties and perceived government failures. It's a fictional, exaggerated commentary rather than a realistic depiction of events.